GO CAN-processes prioritized by the BN model | GO CAN-processes prioritized by the HG enrichment test | ||||
---|---|---|---|---|---|
GO CAN-process | Total gene number | Cancer gene number | GO CAN-process | Total gene number | Cancer gene number |
GO:0006366 transcription from RNA polymerase II promoter | 541 | 52 | GO:0050794 regulation of cellular process | 3,958 | 205 |
GO:0045737 positive regulation of cyclin-dependent protein kinase activity | 3 | 3 | GO:0050789 regulation of biological process | 4,256 | 209 |
GO:0045786 negative regulation of progression through cell cycle | 203 | 41 | GO:0065007 biological regulation | 4,648 | 217 |
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway | 168 | 23 | GO:0043283 biopolymer metabolic process | 5,095 | 226 |
GO:0048268 clathrin cage assembly | 4 | 2 | GO:0000074 regulation of progression through cell cycle | 325 | 53 |
GO:0000718 nucleotide-excision repair, DNA damage removal | 21 | 7 | GO:0051726 regulation of cell cycle | 329 | 53 |
GO:0002903 negative regulation of B cell apoptosis | 2 | 2 | GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 2,501 | 145 |
GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process | 3 | 2 | GO:0031323 regulation of cellular metabolic process | 2,703 | 151 |
GO:0010225 response to UV-C | 2 | 2 | GO:0006350 transcription | 2,540 | 145 |
GO:0006310 DNA recombination | 92 | 13 | GO:0019222 regulation of metabolic process | 2,832 | 154 |
GO:0016571 histone methylation | 6 | 2 | GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 3,771 | 181 |
GO:0060070 Wnt receptor signaling pathway through beta-catenin | 5 | 2 | GO:0045449 regulation of transcription | 2,448 | 140 |
GO:0016573 histone acetylation | 10 | 4 | GO:0006351 transcription, DNA-dependent | 2,360 | 136 |
GO:0045429 positive regulation of nitric oxide biosynthetic process | 5 | 3 | GO:0006355 regulation of transcription, DNA-dependent | 2,302 | 134 |
GO:0006298 mismatch repair | 31 | 7 | GO:0045786 negative regulation of progression through cell cycle | 203 | 41 |
GO:0009168 purine ribonucleoside monophosphate biosynthetic process | 15 | 2 | GO:0032774 RNA biosynthetic process | 2,364 | 136 |
GO:0010332 response to gamma radiation | 3 | 2 | GO:0043170 macromolecule metabolic process | 6,647 | 244 |
GO:0045661 regulation of myoblast differentiation | 6 | 2 | GO:0022402 cell cycle process | 606 | 61 |
GO:0030101 natural killer cell activation | 15 | 3 | GO:0016070 RNA metabolic process | 2,896 | 143 |
GO:0046902 regulation of mitochondrial membrane permeability | 5 | 2 | GO:0007049 cell cycle | 761 | 67 |
GO:0051353 positive regulation of oxidoreductase activity | 5 | 2 | GO:0048523 negative regulation of cellular process | 917 | 73 |
GO:0051898 negative regulation of protein kinase B signaling cascade | 2 | 2 | GO:0048519 negative regulation of biological process | 958 | 73 |
GO:0000910 cytokinesis | 28 | 4 | GO:0044238 primary metabolic process | 7,595 | 254 |
GO:0000075 cell cycle checkpoint | 58 | 14 | GO:0048522 positive regulation of cellular process | 754 | 63 |
GO:0001952 regulation of cell-matrix adhesion | 9 | 6 | GO:0006366 transcription from RNA polymerase II promoter | 541 | 52 |
GO:0042593 glucose homeostasis | 11 | 2 | GO:0048518 positive regulation of biological process | 840 | 65 |
GO:0014065 phosphoinositide 3-kinase cascade | 5 | 3 | GO:0009719 response to endogenous stimulus | 400 | 44 |
Median number | 6 | 3 | Median number | 2,364 | 136 |