Figure 3
From: Evolutionary-new centromeres preferentially emerge within gene deserts
Gene density simulations. The observed density of (a) genes (Refseq), (b) Refseq exons and (c) expressed sequence tag (Est) exons within the corresponding region of the 14 ENCs were compared against a simulated set of 10,000 regions distributed randomly within the human genome (see Materials and methods). A significant depletion of exons and genes was observed.