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Table 1 Gene expression analysis of Egr1 target genes using qRT-PCR of RNA extracted at various time points after UV-C treatment of M12 cells

From: Egr1 regulates the coordinated expression of numerous EGF receptor target genes as identified by ChIP-on-chip

 

Fold change relative to control

 

30 minutes

1 h

2 h

4 h

6 h

Egr2

2.4

6.9

2.33

1.21

2.43

PSD3

17.2

25.3

9.40

4.86

1.05

TOM22

1.1

1.92

0.95

1.70

1.49

H3A

0.9

1.76

1.07

1.28

0.95

BBC3

1.6

0.71

0.23

0.29

2.28

PTPRO

1.1

0.20

0.44

0.31

20.47

AKAP9

1.4

1.26

1.59

0.66

1.00

TNFSF6

4.6

0.70

1.58

0.62

0.62

CysLTR1

2.07

2.28

3.39

0.66

2.81

HK1

1.43

1.28

1.72

0.91

1.10

NME2

0.82

1.35

2.05

1.53

1.13

NME1

1.06

1.21

1.15

1.08

1.29

IFITM2

0.70

0.88

0.66

0.95

0.77

IL11RA

0.78

0.98

0.77

0.86

0.80

ABCC3

0.79

1.06

0.71

0.70

0.81

SLP1

0.80

0.78

1.01

0.64

0.62

CITED4

0.44

0.62

0.52

0.39

0.24

EGFR

0.22

0.53

0.30

0.30

0.18

CDK8

0.73

1.13

0.62

0.42

0.23

HNRPDP

0.67

0.74

0.20

0.10

0.10

GMPS1

0.86

0.60

0.92

0.41

0.35

GSTA3

0.77

0.44

0.79

0.52

0.53

MAP4

0.49

0.59

0.54

0.73

0.41

MAP2

0.28

0.57

0.44

0.46

0.57

HNRPDP

0.67

1.04

0.20

0.10

0.10

GSTA3

0.77

0.44

0.79

0.52

0.53

FosL2

0.37

0.46

0.50

0.13

0.24

BLK

0.73

0.98

0.37

0.87

0.65

RRAS2

0.63

0.95

0.62

0.57

0.32

PAK6

0.78

0.91

0.69

0.42

0.30

CASP7

0.66

0.81

0.54

0.56

0.23

ELF2

0.54

0.61

0.36

0.19

0.16

BMP4

0.53

0.84

0.42

0.24

0.14

DYRK2

0.36

0.50

0.05

0.10

0.10

MAX

0.64

0.72

0.49

0.27

0.24

PTPN13

0.48

0.73

0.42

0.47

0.22

ETS2

0.67

0.70

0.50

0.49

1.09