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Table 1 Top Gene Ontology biological processes in each module
| Module | Activity | Ease score |
|---|---|---|
| Module 1 | Protein biosynthesis | 7.14E-06 |
| Cell development | 2.37E-05 | |
| Cell differentiation | 4.88E-05 | |
| Macromolecule biosynthesis | 8.56E-05 | |
| Cellular nerve ensheathment | 1.11E-04 | |
| Neuron development | 2.22E-04 | |
| Regulation of action potential | 4.37E-04 | |
| Module 2 | Response to other organism | 0.004 |
| Immune response | 0.014 | |
| Defense response | 0.020 | |
| Response to stress | 0.029 | |
| Protein kinase cascade | 0.030 | |
| Integrin-mediated signalling pathway | 0.030 | |
| Myeloid cell differentiation | 0.040 | |
| JAK-STAT cascade | 0.042 | |
| Module 3 | Homophilic cell adhesion | 2.58E-11 |
| Cell-cell adhesion | 2.74E-09 | |
| Nervous system development | 3.44E-09 | |
| Ion transport | 0.007 | |
| Gamma-aminobutyric acid signalling pathway | 0.009 | |
| Secretory pathway | 0.019 | |
| Small GTPase mediated signal transduction | 0.028 | |
| Sodium ion transport | 0.036 | |
| Module 4 | Cellular physiological process | 6.91E-05 |
| Transcription from RNA polymerase II promoter | 0.008 | |
| Protein transport | 0.014 | |
| Post-chaperonin tubulin folding pathway | 0.019 | |
| Ubiquitin cycle | 0.037 | |
| Module 5 | Negative regulation of metabolism | 0.011 |
| Actin filament depolymerization | 0.025 | |
| Barbed-end actin filament capping | 0.025 | |
| Negative regulation of actin filament depolymerization | 0.025 | |
| Negative regulation of protein metabolism | 0.025 | |
| Module 6 | Protein transport | 0.008 |
| Cell organization and biogenesis | 0.011 | |
| Membrane fusion | 0.028 | |
| RNA processing | 0.029 | |
| RNA splicing | 0.042 |
