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Table 1 Top Gene Ontology biological processes in each module

From: Variations in the transcriptome of Alzheimer's disease reveal molecular networks involved in cardiovascular diseases

Module Activity Ease score
Module 1 Protein biosynthesis 7.14E-06
  Cell development 2.37E-05
  Cell differentiation 4.88E-05
  Macromolecule biosynthesis 8.56E-05
  Cellular nerve ensheathment 1.11E-04
  Neuron development 2.22E-04
  Regulation of action potential 4.37E-04
Module 2 Response to other organism 0.004
  Immune response 0.014
  Defense response 0.020
  Response to stress 0.029
  Protein kinase cascade 0.030
  Integrin-mediated signalling pathway 0.030
  Myeloid cell differentiation 0.040
  JAK-STAT cascade 0.042
Module 3 Homophilic cell adhesion 2.58E-11
  Cell-cell adhesion 2.74E-09
  Nervous system development 3.44E-09
  Ion transport 0.007
  Gamma-aminobutyric acid signalling pathway 0.009
  Secretory pathway 0.019
  Small GTPase mediated signal transduction 0.028
  Sodium ion transport 0.036
Module 4 Cellular physiological process 6.91E-05
  Transcription from RNA polymerase II promoter 0.008
  Protein transport 0.014
  Post-chaperonin tubulin folding pathway 0.019
  Ubiquitin cycle 0.037
Module 5 Negative regulation of metabolism 0.011
  Actin filament depolymerization 0.025
  Barbed-end actin filament capping 0.025
  Negative regulation of actin filament depolymerization 0.025
  Negative regulation of protein metabolism 0.025
Module 6 Protein transport 0.008
  Cell organization and biogenesis 0.011
  Membrane fusion 0.028
  RNA processing 0.029
  RNA splicing 0.042
  1. Statistically significant (p < 0.05) biological processes present in each of the six modules of the co-expression network.