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Table 3 Pax2/8 over-expression effect on predicted downstream targets

From: Rapid identification of PAX2/5/8 direct downstream targets in the otic vesicle by combinatorial use of bioinformatics tools

Clone Expression in the otic vesicle Effect upon pax2 misexpression (%)* n
brn2 Yes Repression: 40 28
ccdc102a Yes Activation: 23 34
metrnl Yes Activation: 35 20
sec31l Yes Activation: 44 25
cldn7 Yes Activation: 28 51
  1. *Injected embryos were heat treated during nine somites. Three hours later, GFP positive embryos were fixed.