Figure 3

Performance on PROSITE true positives, false positives, and false negative test sites. We show the (a) true positive (TP), (b) false negative (FN), and (c) false positive (FP) prediction rates for SeqFEATURE (at 95%, 99%, and 100% specificity) and PROSITE on test sites derived from the corresponding PROSITE patterns. The PROSITE values represent the maximum possible for each category. Not all patterns had a false negative or false positive test set. Most of SeqFEATURE's incorrect predictions at 95% and 99% specificity cutoffs arise from poor performance on a small subset of the patterns.