Skip to main content

Table 2 Selected transcripts

From: Translational control plays a prominent role in the hepatocytic differentiation of HepaRG liver progenitor cells

 

Total (fold change)

p-value

Polysome (fold change)

p-value

Contribution from translation

    

SMARCA2

+ 1.46

NS

+ 4.26

0.009

SMARCB1

- 4.00

NS

+ 4.36

0.024

MEF2C

+ 1.31

NS

+ 3.98

0.004

MEF2D

- 1.29

NS

+ 2.35

0.018

NF-KBIA

+ 1.24

NS

+ 2.81

0.027

Oncostatin M receptor/IL6ST

+ 1.24

NS

+ 80.12

0.010

Caspase 8

- 1.92

NS

+ 4.17

0.010

Caspase 9

+ 1.26

NS

+ 3.50

0.025

OAS1

- 1.69

NS

+ 4.82

0.016

IRF3

+ 1.00

NS

+ 5.65

0.034

IFI16

+ 1.90

NS

+ 54.11

0.009

RARA

- 1.19

NS

+ 2.69

0.050

RXRA

+ 1.45

NS

+ 2.17

0.004

RXRB

- 1.23

NS

+ 4.45

0.013

STAT6

+ 1.29

NS

+ 2.99

0.011

EGR1

+ 1.52

NS

+ 12.34

0.050

IGFBP1

+ 1.87

NS

+ 7.38

0.010

MMP3

- 1.10

0.044

+ 6.87

0.047

SLC27A3

+ 2.03

0.043

+ 22.77

0.031

Contribution from transcription

    

PPARA

+ 2.25

0.002

+ 2.49

0.026

PPARD

+ 2.00

0.001

+ 3.80

0.005

CEBPA

+ 3.91

0.050

+ 3.86

0.004

HLF

+ 14.11

0.001

+ 17.09

0.015

ADH1B

+ 354.89

0.021

+ 335.41

0.050

ADH1C

+ 38.86

0.050

+ 27.37

0.003

ADH6

+ 18.22

0.029

+ 46.55

0.050

ApoH

+ 6.49

0.050

+ 7.59

0.008

SERPINA1

+ 2.70

0.007

+ 10.69

0.015

SERPINA4

+ 4.86

0.050

+ 18.58

0.037

SERPINF2

+ 9.82

0.050

+ 2.30

0.000

Complement component 1, s

+ 2.30

0.008

+ 3.40

0.041

Complement component 3

+ 2.28

0.050

+ 2.98

0.042

Complement component 4A

+ 6.65

0.006

+ 7.86

0.025

Complement component 5

+ 3.42

0.039

+ 2.33

0.014

Complement component 6

+ 36.20

0.000

+ 48.42

0.043

Fibrinogen A

+ 15.35

0.017

+ 9.84

0.022

Fibrinogen B

+ 17.13

0.033

+ 15.02

0.033

Fibrinogen G

+ 14.79

0.015

+ 11.55

0.016

TNFSF10/TRAIL

+ 7.08

0.002

+ 5.15

0.007

IL6R

+ 9.30

0.000

+ 15.95

0.012

BMP2

- 2.08

0.000

- 2.00

0.014

PDGFB

- 2.53

0.013

- 2.62

0.003

Translational repression

    

MME

+ 18.16

0.025

+ 1.48

NS

E-cadherin

+ 8.64

0.043

- 1.35

NS

CYP3A4

+ 357.26

NS

+ 11.29

0.015

CYP3A5

+ 20.14

0.012

+ 4.66

NS

CYP2B6

+ 22.78

0.021

+ 2.55

0.016

CYP7B1

+ 2.85

0.048

- 1.49

NS

CYP2A6

+ 2.85

0.002

- 1.51

NS

CYP2C19

+ 17.70

NS

+ 1.35

0.032

CYP4F3

+ 19.58

0.038

+ 5.14

NS

TGFBR2

+ 6.78

0.001

+ 1.15

NS

VEGF

+ 4.67

0.034

- 2.70

NS

Insulin receptor

+ 3.83

<0.001

+ 1.20

NS

Leptin receptor

+ 3.07

0.007

+ 1.34

NS

  1. NS, not significant.