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Table 9 Expression of APC, DC and myeloid signature genes in CD16 cells

From: Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling

   Dendritic cells Myeloid cells   Ratio to DC
Probe set ID Gene BDCA1 BDCA3 pDC Mono Neu CD16 cells CD16 Mono Neu
APC signature genes           
203932_at HLA-DMB 8,636* 7,929 5,894 5,194 173 2,581 0.3 0.6 <0.1
205101_at CIITA 2,803 2,354 724 531 50 226 <0.1 0.2 <0.1
219574_at MARCH1 587 777 544 1,214 58 810 1 2 <0.1
201425_at ALDH2 9,279 7,841 6,034 8,504 706 1,760 0.2 0.9 <0.1
222891_s_at BCL11A 569 747 4,502 310 50 213 <0.1 <0.1 <0.1
205504_at BTK 1,120 822 1,132 1,409 281 1,786 2 1 0.3
202295_s_at CTSH 6,197 2,528 1,211 3,949 75 2,440 0.39 0.6 <0.1
213831_at DQA1 11,535 7,503 5,919 4,701 50 252 <0.1 0.4 <0.1
215536_at DQB2 432 391 157 180 81 52 0.1 0.4 0.2
209312_x_at DRB1 14,608 14,477 13,250 11,915 228 14,007 1 0.8 <0.1
209619_at CD74 12,533 12,210 10,498 9,020 867 7,383 0.6 0.7 <0.1
210042_s_at CTSZ 906 848 692 370 153 673 0.7 0.4 0.2
201560_at CLIC4 920 305 663 3,023 165 354 0.4 3 0.2
217388_s_at KYNU 2,414 1,059 2,204 3,516 50 3,738 2 1 <0.1
203927_at NFKBIE 529 272 232 197 63 290 0.5 0.4 0.1
220998_s_at UNC93B1 966 850 1,938 862 449 1,235 0.6 0.4 0.2
Pan-DC signature genes           
206674_at FLT3 3,032 5,883 2,169 208 <50 <50 <0.1 <0.1 <0.1
219256_s_at SH3TC1 1,263 899 1,128 392 166 858 0.7 0.3 0.1
218617_at TRIT1 1,159 1,246 1,851 509 <50 339 0.2 0.3 <0.1
231810_at BRI3BP 691 735 836 298 146 279 0.3 0.4 0.2
209139_s_at PRKRA 846 1,067 1,440 316 74 497 0.3 0.2 <0.1
225764_at ETV6 2,172 2,432 1,726 1,143 938 941 0.4 0.5 0.4
208837_at TMED3 1,317 1,852 1,859 665 <50 1,022 0.6 0.4 <0.1
219218_at BAHCC1 87 86 250 <50 <50 <50 0.2 0.2 0.2
1552256_a_at SCARB1 325 425 942 165 128 59 <0.1 0.2 0.1
Non-DC signature genes           
219243_at GIMAP4 68 <50 <50 4,404 3,504 1,334 20 65 52
221704_s_at VPS37B 54 <50 <50 593 962 487 9 11 18
204891_s_at LCK <50 <50 <50 92 181 65 - - -
214582_at PDE3B 78 <50 <50 129 625 114 1 2 8
Myeloid signature genes           
225987_at STEAP4 <50 <50 <50 877 6,090 <50 - - -
1552773_at CLEC4D <50 <50 <50 452 520 <50 - - -
222934_s_at CLEC4E 214 124 133 2,837 5,885 229 1 13 28
202974_at MPP1 591 281 377 3,721 2,408 1,341 2 6 4
205098_at CCR1 93 <50 115 3,712 3,627 106 1 32 31
223044_at SLC40A1 769 276 321 5,018 3,444 <50 - 6 4
224341_x_at TLR4 94 <50 <50 1,411 2,869 540 6 15 31
204714_s_at F5 <50 <50 <50 1,392 2,313 <50 - - -
203561_at FCGR2A 1,010 44 51 2,985 7,151 2,857 3 3 7
210772_at FPRL1 <50 <50 <50 389 3,454 70 3 - -
204924_at TLR2 904 211 57 2,870 5,548 1,606 2 3 6
215223_s_at SOD2 1,474 946 528 3,528 7,599 4,236 3 2 5
222218_s_at PILRA 1,168 150 136 2,899 4,035 3,982 3 2 3
210423_s_at SLC11A1 81 60 38 1,767 2,930 3,334 41 22 36
203045_at NINJ1 357 66 71 1,104 3,129 1,934 5 3 9
201669_s_at MARCKS 521 389 <50 2,449 3,224 1,730 3 5 6
207697_x_at LILRB2 1,271 78 774 3,353 3,711 4,903 4 3 3
1553297_a_at CSF3R 1,902 409 156 3,433 6,687 282 0.2 2 4
220088_at C5AR1 56 34 93 2,316 5,099 3,824 41 25 55
221698_s_at CLEC7A 3,229 4,295 79 6,642 7,061 5,680 1 2 2
204204_at SLC31A2 442 187 <50 1,579 2,047 1,671 4 4 5
  1. *Average expression across replicates. Mono, monocyte; neu, neutrophil.
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