Skip to main content

Advertisement

Table 8 Expression of APC, DC and NK signature genes in IKDCs

From: Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling

          Ratio
Probe set ID Gene CD8 DC DN DC CD4 DC pDC cDC IKDC NK IKDC/DC NK/DC IKDC/NK
APC signature genes            
98035_g_at H2-DMb1 2,701* 3,416 4,281 1,105 2,722 179 36 0.2 <0.1 5
92668_at Btk 454 259 331 252 277 91 20 0.4 <0.1 5
94834_at Ctsh 1,606 2,650 2,862 2,993 1,653 129 20 0.1 <0.1 6
94285_at H2-Eb1 8,183 7,761 7,201 5,285 14,120 1,018 74 0.2 <0.1 14
101054_at Cd74 9,094 7,810 7,313 5,158 12,258 1,031 55 0.2 <0.1 19
92633_at Ctsz 520 1,246 1,171 887 750 117 44 0.2 <0.1 3
94256_at Clic4 1,668 1,067 1,234 739 717 440 295 0.6 0.4 1
160781_r_at Unc93b1 683 710 789 301 138 36 22 0.3 0.2 2
Pan-DC signature genes            
95295_s_at Flt3 2,769 2,004 2,231 2,069 2,547 270 45 0.1 <0.1 6
100095_at Scarb1 716 405 333 297 398 125 73 0.4 0.2 2
Non-DC signature genes            
96172_at Gimap4 29 62 20 314 319 5,274 982 263 49 5
92398_at Vps37b 111 139 44 76 56 462 159 11 4 3
161265_f_at Lck 99 80 105 235 199 1,991 366 25 5 5
NK signature genes            
97781_at Ncr1 20 20 20 73 39 1,483 120 20 2 12
97113_at Fasl 20 28 20 22 30 440 263 15 9 2
102272_at Cd160 75 107 62 82 58 780 246 7 2 3
100764_at Il2rb 26 45 40 50 65 84 501 1 8 0.2
99334_at Ifng 20 20 20 29 38 203 109 5 3 2
93931_at Prf1 33 21 35 94 86 839 1,287 9 14 1
92398_at Vps37b 111 139 44 76 56 462 159 11 4 3