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Table 11 Comparison of the transcriptome of mouse GM-CSF BM-derived DCs to that of spleen DCs

From: Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling

   

Ratio to monocytes

Probe set ID

Name

Mono

Mono(2)

MΦ

BM-MΦ

BM-DC

pDC

CD8 DC

CD11b DC

Myeloid signature genes

         

1420804_s_at

Clec4d

4,934

0.65

0.49

0.75

0.41

-

-

-

1420330_at

Clec4e

5,511

0.11

0.22

0.23

0.11

-

-

-

1450808_at

Fpr1

119

1.91

-

5.55

2.41

-

-

-

1452001_at

Nfe2

139

1.44

-

-

3.31

-

-

-

1450919_at

Mpp1

1,888

0.15

2.05

1.75

0.52

0.23

0.09

0.07

1419609_at

Ccr1

403

1.27

4.04

0.53

3.98

0.2

-

-

1417061_at

Slc40a1

2,588

0.68

-

0.56

0.07

0.01

0.01

0.02

1448756_at

S100a9

8,664

1.2

-

0.01

0.99

0

0

-

1417268_at

Cd14

6,745

0.1

0.3

0.6

0.19

0.02

0.01

0.01

1418163_at

Tlr4

464

0.1

0.36

0.93

0.66

-

0.07

0.06

1448620_at

Fcgr3

1,471

2.02

3.56

2.15

2.46

-

0.02

0.07

1422953_at

Fpr-rs2

839

2.04

0.12

0.85

1.58

-

-

0.05

1419132_at

Tlr2

1,763

0.11

0.42

0.24

0.48

0.04

0.1

0.14

1417566_at

Abhd5

170

0.19

0.72

0.86

2.2

0.18

0.45

0.25

1415814_at

Atp6v1b2

1,556

0.22

2.75

1.57

1.43

0.18

0.27

0.24

1427327_at

Pilra

434

1.53

0.16

0.47

2.29

0.1

-

0.21

1418888_a_at

Sepx1

4,416

0.48

0.34

0.31

0.56

0.03

0.04

0.05

1438928_x_at

Ninj1

5,574

0.03

1.3

0.46

0.36

0.03

0.02

0.02

1448881_at

Hp

400

3.19

0.14

0.06

3.09

-

-

-

1449453_at

Bst1

340

1.08

4.97

0.58

1.61

0.21

0.51

-

1419394_s_at

S100a8

10,190

1.37

0.01

0.01

0.66

-

0

-

1437200_at

Fcho2

311

1.09

1.32

1.06

0.76

0.28

0.2

0.33

1418806_at

Csf3r

2,598

0.2

0.14

0.19

0.11

-

-

0.03

1439902_at

C5ar1

317

8.21

0.19

1.63

0.37

-

-

-

1456046_at

Cd93

1,559

0.1

0.49

1.18

0.33

0.02

-

-

1418901_at

Cebpb

3,797

0.14

0.7

0.22

0.42

0.02

0.01

0.02

1420699_at

Clec7a

2,748

0.83

2.62

0.44

1.71

0.08

0.06

0.54

Pan-DC signature genes

         

1419538_at

Flt3

51

0.74

-

-

0.7

16.2

25.32

17.78

1427619_a_at

Sh3tc1

-

>1.1

>6.8

>2.8

>4.9

>5.2

>6.5

>4.6

1424489_a_at

Trit1

54

7.28

0.44

0.76

1.23

9.03

11.53

8.63

1428744_s_at

Bri3bp

161

0.84

0.6

1.44

3.28

6.09

7.24

5.98

1448923_at

Prkra

72

1.28

0.77

2.89

2.57

4.45

7.88

3.63

1434880_at

Etv6

140

5.39

1.52

0.74

1.75

5.79

6.02

7.78

1416108_a_at

Tmed3

154

0.81

3.74

2.63

4.65

10.17

4.48

3

1436633_at

Bahcc1

41

1.77

-

0.83

-

1.8

3.88

2.35

1437378_x_at

Scarb1

97

5.02

1.25

2.61

3.17

7.41

8.27

4.05

cDC signature genes

         

1435108_at

Arhgap22

63

-

-

2.37

0.57

0.59

10.65

4.43

1429168_at

Btbd4

129

0.19

0.27

-

0.47

0.81

3.89

3.8

1425294_at

Slamf8

146

1.06

39.89

1.83

1.77

0.39

8.48

5.27

1453076_at

9130211I03Rik

36

1.61

2.85

1.03

13.11

0.62

30.94

25.64

1436907_at

Nav1

102

1.59

0.74

2.63

1.96

1.21

6.08

13.14

1421210_at

C2ta

125

0.17

1.79

0.19

0.93

1.46

5.94

5.43

1423122_at

Avpi1

150

0.32

-

0.2

0.86

0.61

2.47

7.62

1416627_at

Spint1

-

>1.5

>1.1

-

>22.9

>1.6

>25.7

>30.6

1450667_a_at

Cs

396

2.47

0.9

1.19

3.54

2.83

4.64

4.5

APC signature genes

         

1419744_at

H2-DMb2

451

0.12

0.1

0.08

1.47

0.45

0.48

1.69

1443687_x_at

H2-DMb1

547

0.56

0.13

0.11

1.56

1.06

0.82

3.13

1434955_at

March1

80

32.64

0.83

1.51

3.48

3.73

13.4

8.57

1448143_at

Aldh2

867

0.47

2.14

2.07

1.32

0.95

0.65

0.45

1419406_a_at

Bcl11a

60

1.47

0.34

-

0.71

20.41

7.63

9.19

1422755_at

Btk

416

0.56

0.76

1.3

1.15

0.88

1.45

1.17

1418365_at

Ctsh

1,393

0.81

3.9

2.19

2.15

3.69

1.24

2.16

1417025_at

H2-Eb1

6,385

0.13

0.39

0.04

0.8

0.9

1.31

1.33

1425519_a_at

Cd74

8,377

0.36

0.95

0.2

0.9

0.83

0.97

0.98

1417868_a_at

Ctsz

7,061

0.05

1.16

0.95

0.85

0.5

0.3

0.49

1423393_at

Clic4

2,807

0.07

2.04

0.84

0.57

0.69

0.72

0.67

1430570_at

Kynu

31

1.23

-

-

3.21

12.87

5.16

11.56

1435745_at

5031439G07Rik

356

0.95

0.73

2.76

2.51

3.23

3.14

4.28

1458299_s_at

Nfkbie

767

0.4

0.62

0.1

0.44

1.25

0.65

1.27

1423768_at

Unc93b1

663

0.1

2.27

2.69

1.46

1.2

0.93

0.91

Non-DC signature genes

         

1424375_s_at

Gimap4

362

0.14

0.29

-

0.1

0.11

-

0.11

1424380_at

Vps37b

313

0.44

0.46

0.45

0.26

0.28

0.28

0.27

1425396_a_at

Lck

118

-

0.57

0.2

0.32

0.21

-

0.17

1433694_at

Pde3b

352

0.69

0.15

0.16

0.42

-

0.65

0.35

  1. *Average expression across replicates. Genes for which expression between mouse bone-marrow derived GM-CSF DCs (BM-DCs) and spleen DCs or spleen cDCs varies more than two-fold are shown in bold. BM-MΦ, mouse bone marrow-derived M-CSF macrophages; MΦ, peritoneal mouse macrophages; mono, mouse spleen monocytes from the SB laboratory; mono(2), mouse spleen monocytes from the BP laboratory, as listed in Table 1.
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Genome Biology

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