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Table 1 Overall clinical and biological parameters of 55 obese subjects and 15 lean controls

From: Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity

Phenotype Obese subjects Lean controls
n 55 15
Female/Male 52/3 15/0
Age (years) 40.13 ± 11.67 34.2 ± 8.52
BMI (kg/m2) 44.07 ± 9.06* 23.67 ± 1.51
Glucose homeostasis   
   Glucose (mmol/l) 5.56 ± 1.70 4.82 ± 1.01
   Insulin (μU/ml) 13.51 ± 8.57 7.20 ± 3.49
   QUICKI 0.33 ± 0.05 0.36 ± 0.04
Type 2 diabetes   
   Glycemia > 7 mmol/l or treatment 6 (11%) 0
Lipid homeostasis   
   Cholesterol (mmol/l) 5.22 ± 1.04 4.36 ± 1.05
   HDL cholesterol (mmol/l) 1.27 ± 0.34 1.43 ± 0.23
   Triglycerides (mmol/l) 1.40 ± 0.62 0.45 ± 0.10
Adipokines   
   Leptin (ng/ml) 54.55 ± 19.92 11.24 ± 1.12
   Adiponectin (μg/ml) 7.14 ± 2.87 -
Risk factors   
   HDL < 1.03 mmol/l (M), < 1.29 mmol/l (F) 26 (47%)* 1 (6%)
   Hypertension ≥ 130/85 mmHg 11 (20%) 0
   Glucose ≥ 5.6 mmol/l 17 (31%) 1 (6%)
   Triglycerides ≥ 1.7 mmol/l 11 (20%) 0
Inflammatory factors   
   TNF-α (pg/ml) 1.77 ± 0.62 -
   IL6 (pg/ml) 2.24 ± 1.17 -
   hsCRP (mg/dl) 8.62 ± 10.38 -
   Orosomucoid (g/l) 0.99 ± 0.18 -
   Serum amyloid A (μg/ml) 21.35 ± 22.39 -
Hepatic factors   
   Aspartate aminotransferase (IU/l) 22.66 ± 6.87 -
   Alanine aminotransferase (IU/l) 35.72 ± 18.56 -
   γGT (mg/dl) 45.91 ± 46.43 -
  1. *Bilateral significance p value < 0.05 for the difference between the two groups. Bilateral significance p value < 0.001 for the difference between the two groups. Hyphens indicate parameters that were not available for the lean controls group. F, female; HDL, high-density lipoproteins; M, male.