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Table 1 Overall clinical and biological parameters of 55 obese subjects and 15 lean controls
| Phenotype | Obese subjects | Lean controls |
|---|---|---|
| n | 55 | 15 |
| Female/Male | 52/3 | 15/0 |
| Age (years) | 40.13 ± 11.67 | 34.2 ± 8.52 |
| BMI (kg/m2) | 44.07 ± 9.06* | 23.67 ± 1.51 |
| Glucose homeostasis | ||
| Glucose (mmol/l) | 5.56 ± 1.70 | 4.82 ± 1.01 |
| Insulin (μU/ml) | 13.51 ± 8.57 | 7.20 ± 3.49 |
| QUICKI | 0.33 ± 0.05 | 0.36 ± 0.04 |
| Type 2 diabetes | ||
| Glycemia > 7 mmol/l or treatment | 6 (11%) | 0 |
| Lipid homeostasis | ||
| Cholesterol (mmol/l) | 5.22 ± 1.04 | 4.36 ± 1.05 |
| HDL cholesterol (mmol/l) | 1.27 ± 0.34 | 1.43 ± 0.23 |
| Triglycerides (mmol/l) | 1.40 ± 0.62† | 0.45 ± 0.10 |
| Adipokines | ||
| Leptin (ng/ml) | 54.55 ± 19.92 | 11.24 ± 1.12 |
| Adiponectin (μg/ml) | 7.14 ± 2.87 | - |
| Risk factors | ||
| HDL < 1.03 mmol/l (M), < 1.29 mmol/l (F) | 26 (47%)* | 1 (6%) |
| Hypertension ≥ 130/85 mmHg | 11 (20%) | 0 |
| Glucose ≥ 5.6 mmol/l | 17 (31%) | 1 (6%) |
| Triglycerides ≥ 1.7 mmol/l | 11 (20%) | 0 |
| Inflammatory factors | ||
| TNF-α (pg/ml) | 1.77 ± 0.62 | - |
| IL6 (pg/ml) | 2.24 ± 1.17 | - |
| hsCRP (mg/dl) | 8.62 ± 10.38 | - |
| Orosomucoid (g/l) | 0.99 ± 0.18 | - |
| Serum amyloid A (μg/ml) | 21.35 ± 22.39 | - |
| Hepatic factors | ||
| Aspartate aminotransferase (IU/l) | 22.66 ± 6.87 | - |
| Alanine aminotransferase (IU/l) | 35.72 ± 18.56 | - |
| γGT (mg/dl) | 45.91 ± 46.43 | - |
