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Figure 14 | Genome Biology

Figure 14

From: Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity

Figure 14

Macrophages promote ECM component secretion by pre-adipocytes. (a-d) Immunofluorescence analysis of pre-adipocytes cultivated with control (a,c) or AcMC-conditioned media (b,d) reveals that they express type 1 collagen (b, green staining, arrows) and fibronectin (d, red staining) in the latter condition. (e) Electron microscopy picture of an adipose tissue macrophage ('m') shows its collocation with collagen fibers ('c') and a lipid droplet ('l'). (a-d) Representative images of five independent experiments.

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