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Figure 6 | Genome Biology

Figure 6

From: Germline mutagenesis mediated by Sleeping Beautytransposon system in mice

Figure 6

A new version of transposon vector for gene trapping. Transcription of an endogenous gene is disrupted and β-galactosidase (β-gal) is expressed. Transcription by the CAG promoter generates a chimeric transcript of the green fluorescent protein (GFP) and the endogenous gene. IRES, internal ribosome entry site; pA, poly(A) addition signal; SA, splice acceptor; SD, splice donor.

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