DetectiV: visualization, normalization and significance testing for pathogen-detection microarray data

Table 1 DetectiV normalization methods

Method	Normalized statistic	Terms
Median	$\log_{2} (x_{j}^{i} / {\tilde{x}}_{j})$	Where $x_{j}^{i}$ is the value for probe i on array j and ${\tilde{x}}_{j}$ is the median value for all probes on array j
Control	$\log_{2} (x_{j}^{i} / {\bar{c}}_{j})$	Where $x_{j}^{i}$ is the value for probe i on array j and ${\bar{c}}_{j}$ is the mean value for control oligo c on array j
Array	$\log_{2} (x_{j}^{i} / x_{c}^{i})$	Where $x_{j}^{i}$ is the value for probe i on array j and $x_{c}^{i}$ is the value for probe i on control array/channel c

ISSN: 1474-760X