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Table 3 Top 20 categories for sensitivity to gefitinib

From: The LeFE algorithm: embracing the complexity of gene expression in the interpretation of microarray data

Rank Category FDR
1 Androgen up genes na 0.347
2 EGF receptor signaling pathway BioCarta 0.408
3 MAP00100 Sterol biosynthesis GenMAPP 0.531
4 Epidermal growth factor receptor signaling pathway (GO:0007173) 0.531
5 G1/S transition of mitotic cell cycle (GO:0000082) 0.628
6 positive regulation of I-kappaB kinase/NF-kappaB cascade (GO:0043123) 0.628
7 Cell-cell adhesion (GO:0016337) 0.748
8 Aspartate catabolism (GO:0006533) 0.915
9 Calcium-independent cell-cell adhesion (GO:0016338) 0.915
10 Regulation of glycolysis (GO:0006110) 0.915
11 Detection of pest, pathogen or parasite (GO:0009596) 0.915
12 MalatePathway BLACK 0.915
12 RarPathway BLACK 0.915
14 Epidermis development (GO:0008544) 0.931
14 Regulation of endocytosis (GO:0030100) 0.931
16 NFKB reduced Hinata et al 2003 0.998
17 mRNA editing (GO:0006381) ~1
17 EMT DOWN Jechlinger et al 2003 ~1
19 Chloride transport (GO:0006821) ~1
19 Induction of apoptosis by intracellular signals (GO:0008629) ~1
  1. FDR, false discovery rate; GO, Gene Ontology; LeFE, Learner of Functional Enrichment.