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Table 1 Top 20 LeFE Categories for current versus never-smokers classification

From: The LeFE algorithm: embracing the complexity of gene expression in the interpretation of microarray data

Rank Category FDR
1 Electron transporter activity BioCarta ~0
1 Carbohydrate metabolism (GO:0005975) ~0
1 Electron transport BioCarta ~0
1 Glutathione metabolism GenMAPP ~0
1 Pentose Phosphate Pathway BLACK ~0
6 Xenobiotic metabolism (GO:0006805) 0.016
6 O Glycans biosynthesis GenMAPP 0.016
8 PentosePathway BLACK 0.045
9 Protein amino acid O-linked glycosylation (GO:0006493) 0.069
10 Pentose phosphate pathway GenMAPP 0.094
10 Gamma hexachlorocyclohexane degradation GenMAPP 0.094
12 Tyrosine metabolism GenMAPP 0.097
13 Cysteine metabolism (GO:0006534) 0.105
13 G1pPathway BLACK 0.105
13 T cell differentiation (GO:0030217) 0.105
13 Fatty acid metabolism BioCarta 0.105
17 Retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) 0.11
18 Aldehyde metabolism (GO:0006081) 0.11
19 Digestion (GO:0007586) 0.114
19 MAP00051 Fructose and mannose metabolism GenMAPP 0.114
  1. FDR, false discovery rate; GO, Gene Ontology; LeFE, Learner of Functional Enrichment.