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Table 3 Across experiment comparison of protein subsets associated with systematic error

From: Coverage and error models of protein-protein interaction data by directed graph analysis

 

Not in Krogan et al. [11]

In Krogan et al. [11]

Not in Gavin et al. [10]

651

45

In Gavin et al. [10]

26

8

 

P = 1.8 × 10-3

Odds ratio = 4.44

  1. This table represents the comparison of proteins affected by a reciprocity artifact from the datasets of Gavin and coworkers [10] and Krogan and colleagues [11] as well. Before conducting the binomial test, the data graphs were restricted to the nodes common to the viable bait/prey (VBP) sets of both experiments. Again, only those proteins identified by the binomial test in which in-degree is much larger than the out-degree is compared. Both the P value and odds ratio, obtained using the hypergeometric distribution, show a strong association between the two sets of proteins.