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Figure 3 | Genome Biology

Figure 3

From: Coverage and error models of protein-protein interaction data by directed graph analysis

Figure 3

Two-sided binomial test on the data from Krogan and coworkers [11]. The scatter-plot shows (o p ,i p ) for each p ∈ VBP from the report by Krogan and coworkers [11] (axes are scaled by the square root). The proteins that fall outside of the diagonal band exhibit high asymmetry in unreciprocated degree. This figure shows a graphical representation of a two-sided binomial test. The points above and below the diagonal band are proteins for which we reject the null hypothesis that the distribution of unreciprocated edges is governed by B(n p , 1 2 MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfeBSjuyZL2yd9gzLbvyNv2Caerbhv2BYDwAHbqedmvETj2BSbqee0evGueE0jxyaibaiKI8=vI8tuQ8FMI8Gi=hEeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=vr0dc8meaabaqaciGacaGaaeqabaqadeqadaaakeaadaWcaaqaaiaaigdaaeaacaaIYaaaaaaa@34B4@ ). For the purpose of visualization, small random offsets were added to the discrete coordinates of the data points by the R function jitter. VBP, viable bait/prey.

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