Quantitative genomics of locomotor behavior in Drosophila melanogaster

Table 2 Functional tests of candidate genes

Line	Gene	Mean locomotor reactivity (± SE)	F_1,112	P value	Human ortholog
BG01127	muscleblind	21.63 ± 1.47	37.47	< 0.0001	MBLN1
BG01259	Ken and barbie	23.43 ± 1.32	17.26	< 0.0001	N/A
BG01697	CG33523	24.13 ± 1.30	22.08	< 0.0001	N/A
BG01761	Amphiphysin	26.80 ± 0.93	5.66	0.019	AMPH
BG01863	Cysteine string protein	20.50 ± 1.54	46.97	< 0.0001	DNAJC5B
BG02106	CG31145	26.40 ± 0.97	2.03	0.157	FAM20A
BG02109	tartan	26.15 ± 0.92	1.16	0.096	N/A
BG02121	center divider	26.80 ± 0.77	1.16	0.285	N/A
BG02676	CG10990	25.30 ± 1.20	16.86	< 0.0001	PDCD4
BG02715	nebbish	25.25 ± 1.27	14.41	< 0.0001	KIF14

The mean locomotor reactivity of the Canton S B control strain is 28.50 ± 0.20 s. Bonferroni significance threshold = 0.005. Human orthologs have homology scores of > 0.93 and Bootstrap scores of > 93%. N/A, not applicable; SE, standard error.

ISSN: 1474-760X