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Table 2 Functional tests of candidate genes

From: Quantitative genomics of locomotor behavior in Drosophila melanogaster

Line Gene Mean locomotor reactivity (± SE) F1,112 P value Human ortholog
BG01127 muscleblind 21.63 ± 1.47 37.47 < 0.0001 MBLN1
BG01259 Ken and barbie 23.43 ± 1.32 17.26 < 0.0001 N/A
BG01697 CG33523 24.13 ± 1.30 22.08 < 0.0001 N/A
BG01761 Amphiphysin 26.80 ± 0.93 5.66 0.019 AMPH
BG01863 Cysteine string protein 20.50 ± 1.54 46.97 < 0.0001 DNAJC5B
BG02106 CG31145 26.40 ± 0.97 2.03 0.157 FAM20A
BG02109 tartan 26.15 ± 0.92 1.16 0.096 N/A
BG02121 center divider 26.80 ± 0.77 1.16 0.285 N/A
BG02676 CG10990 25.30 ± 1.20 16.86 < 0.0001 PDCD4
BG02715 nebbish 25.25 ± 1.27 14.41 < 0.0001 KIF14
  1. The mean locomotor reactivity of the Canton S B control strain is 28.50 ± 0.20 s. Bonferroni significance threshold = 0.005. Human orthologs have homology scores of > 0.93 and Bootstrap scores of > 93%. N/A, not applicable; SE, standard error.