Table 1 Differentially represented Gene Ontology categories
From: Quantitative genomics of locomotor behavior in Drosophila melanogaster
Category | Term | Count* | Percent†| P value‡ |
|---|---|---|---|---|
Biological process | Lipid metabolism | 110 | 6.10 | 3.10E-09 |
| Â | Steroid metabolism | 41 | 2.30 | 9.90E-09 |
| Â | Cellular lipid metabolism | 78 | 4.30 | 9.30E-08 |
| Â | Response to toxin | 34 | 1.90 | 4.20E-06 |
| Â | Response to biotic stimulus | 94 | 5.20 | 7.90E-06 |
| Â | Transport | 309 | 17.10 | 9.20E-06 |
| Â | Defense response | 92 | 5.10 | 9.60E-06 |
| Â | Response to chemical stimulus | 66 | 3.60 | 9.80E-06 |
| Â | Response to abiotic stimulus | 84 | 4.60 | 1.20E-05 |
| Â | Localization | 352 | 19.40 | 1.40E-05 |
| Â | Metabolism | 799 | 44.10 | 1.70E-05 |
| Â | DNA-dependent DNA replication | 22 | 1.20 | 3.60E-05 |
| Â | Establishment of localization | 340 | 18.80 | 3.70E-05 |
| Â | Physiological process | 1,041 | 57.50 | 4.30E-05 |
| Â | DNA replication | 36 | 2.00 | 1.60E-04 |
| Â | Cellular physiological process | 958 | 52.90 | 2.50E-04 |
| Â | Secretion | 48 | 2.70 | 2.80E-04 |
| Â | Electron transport | 74 | 4.10 | 3.00E-04 |
| Â | Response to stress | 66 | 3.60 | 3.20E-04 |
| Â | Response to stimulus | 191 | 10.50 | 3.50E-04 |
| Â | Secretory pathway | 45 | 2.50 | 4.30E-04 |
| Â | Response to endogenous stimulus | 31 | 1.70 | 7.80E-04 |
| Â | Response to DNA damage stimulus | 28 | 1.50 | 8.10E-04 |
| Â | Sleep | 7 | 0.40 | 1.00E-03 |
| Â | Primary metabolism | 705 | 38.90 | 1.50E-03 |
| Â | Protein complex assembly | 28 | 1.50 | 2.60E-03 |
| Â | Intracellular transport | 99 | 5.50 | 2.90E-03 |
| Â | DNA repair | 25 | 1.40 | 2.90E-03 |
| Â | Intracellular protein transport | 80 | 4.40 | 3.90E-03 |
| Â | Regulation of neurotransmitter levels | 26 | 1.40 | 4.20E-03 |
| Â | Cell organization and biogenesis | 221 | 12.20 | 4.40E-03 |
| Â | Cellular localization | 101 | 5.60 | 4.50E-03 |
| Â | Protein localization | 91 | 5.00 | 4.60E-03 |
| Â | Heterophilic cell adhesion | 6 | 0.30 | 4.70E-03 |
| Â | Proteolysis | 129 | 7.10 | 5.20E-03 |
| Â | Establishment of cellular localization | 100 | 5.50 | 5.70E-03 |
| Â | Oxygen and reactive oxygen species metabolism | 18 | 1.00 | 6.20E-03 |
| Â | Sulfur metabolism | 15 | 0.80 | 7.00E-03 |
| Â | Generation of precursor metabolites and energy | 92 | 5.10 | 7.50E-03 |
| Â | Cellular metabolism | 711 | 39.30 | 7.70E-03 |
| Â | Neurotransmitter secretion | 23 | 1.30 | 8.00E-03 |
| Â | Regulated secretory pathway | 23 | 1.30 | 8.00E-03 |
| Â | mRNA export from nucleus | 7 | 0.40 | 8.40E-03 |
| Â | Establishment of protein localization | 82 | 4.50 | 8.90E-03 |
| Â | Sterol metabolism | 10 | 0.60 | 9.00E-03 |
| Â | Macromolecule metabolism | 498 | 27.50 | 9.70E-03 |
| Â | Chromosome condensation | 9 | 0.50 | 1.00E-02 |
| Â | Nuclear transport | 16 | 0.90 | 1.00E-02 |
Molecular function | Catalytic activity | 639 | 35.30 | 3.60E-10 |
| Â | Monooxygenase activity | 38 | 2.10 | 1.50E-07 |
| Â | Oxidoreductase activity | 131 | 7.20 | 1.40E-06 |
| Â | Protein binding | 693 | 38.30 | 2.60E-06 |
| Â | Transporter activity | 208 | 11.50 | 1.40E-05 |
| Â | Electron transporter activity | 49 | 2.70 | 9.40E-05 |
| Â | Hydrolase activity | 294 | 16.20 | 2.70E-04 |
| Â | Sequence-specific DNA binding | 12 | 0.70 | 4.40E-04 |
| Â | Tetrapyrrole binding | 16 | 0.90 | 1.30E-03 |
| Â | Heme binding | 16 | 0.90 | 1.30E-03 |
| Â | Binding | 990 | 54.70 | 1.80E-03 |
| Â | Carbon-carbon lyase activity | 14 | 0.80 | 2.60E-03 |
| Â | Electrochemical potential-driven transporter activity | 43 | 2.40 | 2.80E-03 |
| Â | Porter activity | 43 | 2.40 | 2.80E-03 |
| Â | Calmodulin binding | 18 | 1.00 | 3.60E-03 |
| Â | Carbohydrate transporter activity | 19 | 1.00 | 5.10E-03 |
| Â | Phosphoric monoester hydrolase activity | 36 | 2.00 | 6.50E-03 |
| Â | DNA-directed DNA polymerase activity | 10 | 0.60 | 6.60E-03 |
| Â | Sugar porter activity | 12 | 0.70 | 7.40E-03 |
| Â | Glutathione transferase activity | 11 | 0.60 | 8.70E-03 |
| Â | Sugar transporter activity | 13 | 0.70 | 1.00E-02 |
Cellular component | Microsome | 31 | 1.70 | 5.80E-10 |
| Â | Vesicular fraction | 31 | 1.70 | 5.80E-10 |
| Â | Cell fraction | 34 | 1.90 | 1.20E-09 |
| Â | Membrane fraction | 33 | 1.80 | 2.10E-09 |
| Â | Clathrin coat | 9 | 0.50 | 3.80E-04 |
| Â | Replication fork | 9 | 0.50 | 3.80E-04 |
| Â | Coated membrane | 11 | 0.60 | 6.70E-04 |
| Â | Membrane coat | 11 | 0.60 | 6.70E-04 |
| Â | Clathrin vesicle coat | 8 | 0.40 | 1.10E-03 |
| Â | Clathrin coated vesicle membrane | 8 | 0.40 | 1.10E-03 |
| Â | Golgi apparatus | 24 | 1.30 | 1.40E-03 |
| Â | Coated pit | 5 | 0.30 | 1.50E-03 |
| Â | Cell | 673 | 37.20 | 1.60E-03 |
| Â | Cytoplasmic vesicle membrane | 10 | 0.60 | 1.70E-03 |
| Â | Vesicle coat | 10 | 0.60 | 1.70E-03 |
| Â | Coated vesicle membrane | 10 | 0.60 | 1.70E-03 |
| Â | Cytoplasm | 239 | 13.20 | 2.90E-03 |
| Â | Membrane | 295 | 16.30 | 3.00E-03 |
| Â | Plasma membrane | 83 | 4.60 | 3.80E-03 |
| Â | Alpha DNA polymerase | 4 | 0.20 | 4.30E-03 |
| Â | Chromosome | 40 | 2.20 | 5.00E-03 |