|
Cluster
|
n
|
Outcome
|
LI
|
ER-
|
|---|
| | |
Good
|
Poor
|
High
|
Low
|
Luminal B
|
Luminal A
|
Normal
|
Basal
|
HER2
|
|---|
|
CC+/IR+
|
39
|
25
|
14
|
7
|
2
|
0
|
0
|
0
|
38
|
1
|
|
CC+
|
37
|
18
|
17
|
3
|
5
|
0
|
0
|
1
|
33
|
3
|
|
ECM+
|
45
|
26
|
18
|
1
|
14
|
0
|
9
|
9
|
22
|
5
|
|
SR+
|
36
|
16
|
20
|
2
|
4
|
1
|
1
|
0
|
2
|
32
|
|
IR+
|
29
|
23
|
6
|
6
|
6
|
0
|
4
|
2
|
9
|
14
|
- For the five clusters of Figure 2a, we give the number of samples per cluster (n) and their distributions over good/poor outcome, high/low lymphocytic infiltration (LI) score, and intrinsic subtypes as determined by the single sample predictor (SSP) classifier. Clusters were labeled by the main Gene Ontology of genes over-expressed in the group: CC+ (cell cycle), CC+/IR+ (cell cycle and immune response), ECM+ (extracellular matrix), SR+ (steroid hormone response), and IR+ (immune response). ER, estrogen receptor.
