Expression profiles of selected prognostic markers in ER- breast cancer. Expression profile (on a log2 scale) of selected prognostic markers (a) IGLC2 and (b) C1QA in the integrated cohort of 186 ER- tumours (NKI2 + EMC + NCH), and in the validation cohorts UPP and JRH-2. Good outcome samples are shown in green, and poor outcome samples in blue. Clusters were inferred using the variational Bayesian approach in NKI2 + EMC + NCH and the pam algorithm in the UPP and JRH-2 cohorts. Infered clusters are indicated by different shapes (triangles and diamonds). ER, estrogen receptor; pam, partitioning around medoids.