Complexity, connectivity, and duplicability as barriers to lateral gene transfer

Table 2 Mean phylogenetic discordant sequence score for different subsets of E. coli proteins

Group	Number of proteins	Mean PDS (SEM)	Pair-wise significance of comparison (p)
Monomers	137	0.807 (0.028)	0.056
Homo-oligomers	459	0.758 (0.017)
Monomers + homo-oligomers	596	0.769 (0.015)	0.164
Hetero-oligomers	407	0.794 (0.018)
Singletons	2,382	0.739 (0.007)	<0.00001
Non-singletons	1,920	0.678 (0.009)
1 interaction (SP*)	150	0.766 (0.029)	0.00005
>1 interaction (SP)	641	0.845 (0.013)
1 interaction (PD^†)	368	0.732 (0.02)	0.086
>1 interaction (PD)	1,897	0.711 (0.009)	0.086

* Interaction subsets based on SwissProt data. ^†Interaction subsets based on pull-down data. SEM, standard error of the mean.

ISSN: 1474-760X