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Figure 4 | Genome Biology

Figure 4

From: Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns

Figure 4

Intron flank conservation of TG-AG splice acceptor tandems. Orthologous human/mouse intron-exon boundaries involving TG splice sites are displayed in a two-dimensional plot according to two properties: horizontal axis = sequence identity of 50 nt sequence upstream of both splice sites; vertical axis = relative abundance of the TG-derived splice variant, as reflected by the fraction of TG-spliced ESTs (except for CACN1A1, where the data are taken from Table 2). Data points are labeled with the gene symbol if the conservation score and/or the fraction of TG-derived splice variant are significantly high. Conservation properties of canonical introns are indicated by shaded intervals: black line = median; dark gray = 66% percentile; light gray = 90% percentile.

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