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Table 2 Size and composition of BAC groups in the MegaBAC analysis on the human genome and contribution to these groups by BACs present in the tail-to-tail groups from mapping onto the cow and/or dog genomes.

From: Using comparative genomics to reorder the human genome sequence into a virtual sheep genome

MegaBAC group

MegaBAC analysis

BACs in tail-to-tail group in cow and/or dog

 

Number of BACs

% False positiona

Clustered (n [%])

% of MegaBAC group

Fold enrichment clustered

Cow or dog (n)

Dog (n)

Cow (n)

Tail-to-tail

84,624

0.056%

NA (NA)

78%

na

66,111

56,598

29,424

Tail-to-tail outsize

1,629

48%

451 (28%)

21%

2.4

350

195

202

Tail-to-head

2,477

2%

1,811 (73%)

36%

1

903

460

578

Tail-to-head outsize

4,134

38%

1,295 (31%)

18%

2

762

380

498

Head-to-head

245

10%

183 (75%)

7.8%

0.6

19

12

9

Head-to-head outsize

1,356

58%

47 (3.5%)

14%

0.7

197

63

159

Break

27,829

~100%

NA (NA)

9.4%

na

2,623

944

1,834

Unpaired

52,663b

na

NA (NA)

0.1%c

na

38

12

28

No hits

18,113

na

NA (NA)

na

na

0

0

0

  1. aCalculated from randomisation of the MegaBAC analysis dataset. bIncludes 13,857 BACs with only one sequenced end. cPercentage of BACs with both ends sequenced, but only one end positioned in MegaBAC analysis. BAC, bacterial artificial chromosome; NA, not applicable.