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Figure 4 | Genome Biology

Figure 4

From: Using comparative genomics to reorder the human genome sequence into a virtual sheep genome

Figure 4

Examples of detailed views of the sheep BAC mapping information on the human and virtual sheep genomes. (a) A short section of human chromosome HSA3 from 0 to 1 Mb, showing human RefSeq genes, tail-to-head and tail-to-tail MegaBAC analysis BACs, and cMegaBAC-CGCs. (b) A short section of human chromosome HSA3 from 23 to 23.8 Mb, showing tracks as above and the Dog net level 2 track. (c) A region of low confidence in the virtual sheep genome. The region is from sheep chromosome OAR9. Tracks shown are the human RefSeq genes from NCBI, sheep markers from the Sheep Map version 4.6, the cMegaBACs, the tail-to-tail BACs from the MegaBAC analysis, and unpaired-in-cow, shown as high (single hits to the cow genome with the parameters used) and low (more than one hit to the cow genome with the parameters used) confidence sets. The dotted lines in the unpaired tracks indicate the predicted extent of the BACs in the genome assuming all BACs are 184 kb long (the average length of the BACs in the library). All images are from genome databases displayed using Gbrowse [45]. BAC, bacterial artificial chromosome; CGC, comparative genome contig; HSA, human chromosome; kb, kilobase; Mb, megabase; NCBI, National Center for Biotechnology Information; OAR, sheep chromosome.

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