Human subtelomeric duplicon structure and organization

Table 1 Large subtelomere-specific duplicons

Subtel block	Telomere	Size (kb)	Duplicated blocks	Percent identity	Named transcripts
1	1p	25	4	97.15-98.42	Sim to protein phosphatase 1 inhibitor subunit 2
2	15q	88	7	97.84-98.33	OR4F3, OR4F4, OR4F5, OR4F29, OR4F21, OR4F16, OR4F17, C6orf88
3	1p	35	1	97
5	2p	17	5	90.49-92.00	Sim to RPL23AP7
6	3q	38	5	97.15-97.89	Sim to RPL23AP7
6'	11p	11	1	97.98	RYD5
7	4q	28	1	*	DUX4
8	4q	14	6	91.33-94.60	TUBB4q
10	2q	49	1	96.47	FBXO25
11	9q	36	6	91.26 - 95.68	IL9R
12	12p	15	1	97.89	IQSEC3

* Block 7 corresponds to the D4Z4 tandem repeat on the 4q and 10q subtelomeres, for which no percent identity is calculated because of the very large number and diverse % identities of the BLAST alignments among tandem D4Z4 repeats.

ISSN: 1474-760X