Figure 1

Duplicon substructure of the 7p subtelomere region. The most distal 140 kb of the chromosome 7p reference sequence is shown oriented with the telomeric end on the left (34 kb of unsequenced 7p DNA lie beyond the sequenced region shown, and the remaining 350 kb of the 7p subtelomere region centromeric to that shown does not contain duplicated DNA). The distance from the end of the sequence to the start of the terminal repeat array is indicated by the vertical arrow at the telomeric end of the sequence. The position and 5'-3' G-strand orientation of (TTAGGG)n elements are shown as black arrows. Duplicated genomic segments are identified by chromosome (color) and whether they are subtelomeric (bounded rectangles), non-telomeric (unbounded rectangles), or intra-chromosomal (located above the subtelomere coordinates).