Figure 8
From: Meta-analysis of primary target genes of peroxisome proliferator-activated receptors
Conservation patterns across multiple species. The genes ACOX1 and ANGPLT4 from chicken, chimpanzee, dog, rat and zebrafish were also analyzed. Putative PPREs (red boxes, no conservation; orange boxes, within conserved area; yellow boxes, conserved in human; pink boxes, conserved in mouse) were identified by in silico screening of the genomic sequences. For each of the predicted PPREs, the calculated binding strengths of PPARα (green), PPARγ (dark blue) and PPARβ/δ (light blue) in reference to a consensus DR1-type PPRE are represented by column height. All putative PPRE sequences are available on request.