Cell-specific microarray profiling experiments reveal a comprehensive picture of gene expression in the C. elegans nervous system

Table 1 Expression of promoter-GFP reporters for transcripts enriched in the embryonic pan-neural, larval pan-neural or A-class motor neuron datasets

			Pan-neural			A-class
Cosmid	Gene	Protein	EP fold change	LP fold change	In neurons*	Fold change	UNC-4 neuron(s)*
C01G6.4		Predicted E3 ubiquitin ligase	1.8	-	√	-	VA, DA
VF11C1L.1	ppk-3	PIP kinase	1.8	-	√	-	VA, DA
C25D7.8		Novel	1.9	-	√	-	VA, DA
F08G12.1			3.0	-	√	-	VA, DA
M79.1	abl-1	Abelson kinase	2.3	-	√	-	VA, DA
F25G6.4	acr-15	Acetylcholine receptor	-	4.9	√	-	VA, DA
T27A1.6	mab-9	Transcription factor	-	1.7	√	-	DA
F39G3.8	tig-2	TGF-β	-	1.8	√	-	VA, DA
T19C4.5		Novel	-	2.0		-
CC4.2	nlp-15	Neuropeptide	-	6.5	√	-
C18H9.7	rpy-1	Rapsyn	-	2.7	√	-	DA
Y71D11A.5		Ligand-gated ion channel	2.1	1.8	√	-
C04E12.7		Phospholipid scramblase	-	3.2	√	1.8	VA, DA
F36A2.4	twk-30	K⁺ channel	-	2.1	√	5.1	VA, DA
Y71H9A.3	sto-4	Stomatin	-	3.0	√	1.6	VA
F29G6.2		Novel	-	3.2	√	1.6	VA, DA,SAB, I5, AVF
C44B11.3	mec-12	Alpha-tubulin	-	5.9	√	1.9	VA, DA
T23D8.2	tsp-7	Tetraspanin	-	3.5	√	4.8	VA, DA
T05C12.2	acr-14	Acetylcholine receptor	-	1.5	√	3.1	DA
F33D4.3	flp-13	Neuropeptide	-	7.1	√	7.9	I5
C11D2.6	nca-1	Ca⁺⁺ channel	-	2.3	√	2.2	VA, DA
E03D2.2	nlp-9	Neuropeptide	-	3.1	√	2.5	VA
F55C12.4		Novel	-	3.5	√	2.1	DA
F43C9.4	mig-13	CUB domain	-	1.8	√	2.8	VA, DA
F39B2.8		Predicted membrane protein	1.7	3.5	√	2.1	VA, DA
K02E10.8	syg-1	Ig domain	1.8	1.8	√	1.8	VA, DA
ZC21.2	trp-1	Ca⁺⁺ channel	1.9	2.2	√	1.9	VA, DA
Y47D3B.2a	nlp-21	Neuropeptide	3.9	8.3	√	3.7	VA, DA
F09C3.2		Phosphatase	1.9	2.7	√	1.7	VA, DA
T27E9.9		Ligand-gated ion channel	2.3	4.0	√	3.1
Y34D9B.1	mig-1	Frizzled-like	-	-	√	1.6	VA, DA

*GFP expression in neurons (check mark), and in A-class motor neurons (DA, VA, SAB, I5). GFP expression was typically determined in L2 larvae. Full expression patterns can be found in Additional data file 17. Expression patterns for some of these GFP reporters have been previously reported: T27A1.6, F39G3.8, T19C4.5, CC4.2, C18H9.7, F36A2.4, F29G6.2, T23D8.2, T05C12.2, F33D4.3, C11D2.6, E03D2.2, F55C12.4, F43C9.4, K02E10.8, ZC21.2, Y47D3B.2a, F09C3.2 [5]; F33D4.3 [43]; CC4.2, E03D2.2 [96]; F36A2.4, [121]; F43C9.4, [122]. Y47D3B.2a, [123].

ISSN: 1474-760X