|
Model
|
Mm strain
|
N
|
Tumor-generating laboratory
|
|---|
|
Azoxymethane (AOM)
|
A × B
|
14
|
Threadgill
|
|
Apc
Min/+
|
(SWR × B6) F1
|
2
|
Dove
|
|
Apc
Min/+
|
(BR × B6) F1
|
2
|
Dove
|
|
Apc
Min/+
|
C57BL/6
|
5
|
Groden
|
|
Smad3
-/-
|
129
|
6
|
Graff
|
|
Smad3
-/-
|
129
|
7
|
Coffey
|
|
Tgfb1-/-; Rag2-/-
|
C57BL/6
|
3
|
Doetschman
|
- Tumors from four established mouse models of CRC (ApcMin/+, AOM, Smad3-/- and Tgfb1-/-; Rag2-/- were analyzed. The table provides details on the mouse strains used for the four models, as well as information on the number of samples generated per model and sample-originating laboratory.
