Morphine effects on striatal transcriptome in mice

Table 1 Summary of genotype-dependent differences in striatal gene expression profile between mouse strains

Fold change of mean mRNA level^a	129P3/J strain	C57BL/6J strain	DBA/2J strain	SWR/J strain
>1.2	906 (+295)^b	925 (+511)	888 (+277)	924 (+391)
>1.5	261 (+50)	230 (+108)	288 (+53)	256 (+60)
>2	99 (+9)	68 (+29)	111 (+14)	89 (+9)
>3	43	20 (+6)	48 (+5)	36

The mouse strains evaluated were 129P3/J, C57BL/6J, DBA/2J, and SWR/J. ^aFold change over mean mRNA level from all four strains for 3,457 significantly different probe sets. Relative expression levels were computed from MBEI perfect match/mismatch (PM/MM) data. ^bTotal numbers of probe sets are presented. In addition, numbers of transcripts with increased level comparing to mean are included in parentheses.

ISSN: 1474-760X