| Â | C1 | C2 | C3 | S1 | S2 | S3 |
|---|
Naef model | 0.785 | 0.793 | 0.789 | 0.799 | 0.788 | 0.770 |
Zhang model | 0.820 | 0.829 | 0.826 | 0.834 | 0.827 | 0.808 |
Naef scaling | 0.782 | 0.790 | 0.788 | 0.796 | 0.787 | 0.766 |
Zhang scaling | 0.821 | 0.830 | 0.828 | 0.835 | 0.830 | 0.810 |
- The table shows the correlation coefficients between observed intensities for the empty probes on the three control (C) and spike-in (S) experiments and the corresponding model predictions. The 'model' entries correspond to the correlation between observations and predicted values for refinements of models, including the affinity, binding energy and weights parameters. The 'scaling' entries refer to the correlation between the observation from the cross-validation set and the predicted values obtained by refining restricted models, where affinities, binding energies and weights are kept constant at values obtained from the fits on the complete models (see Materials and methods). The agreement between the values of correlation coefficients from both types of refinement suggests that the affinity, binding energy and weights parameters are general and do not depend on the sequence or the experiment.
