Figure 6

Specificity and sensitivity for simulated data. Results averaged over 25 simulated data sets, each of size approximately 100 Kb, that are aligned by TBA. (a) Specificity with respect to the same species: for each suspicious region reported by StatSigMA-w, the histogram shows the percentage of its columns for which the species reported as suspicious is actually misaligned by TBA. (b) Specificity with respect to any species: for each suspicious region reported by StatSigMA-w, the histogram shows the percentage of its columns for which any species is actually misaligned by TBA. (c) Sensitivity with respect to the same species: for each misalignment region, the histogram shows the percentage of its columns for which StatSigMA-w reports a p-value at least 0.1 for a branch attributable to the misaligned species. (d) Sensitivity with respect to any species: for each misalignment region, the histogram shows the percentage of its columns for which StatSigMA-w reports a p-value at least 0.1 for any branch.