Toxicogenomic analysis of Caenorhabditis elegans reveals novel genes and pathways involved in the resistance to cadmium toxicity

Table 3 Published RNAi phenotypes of down-regulated genes

Target gene name	Description	24 h fold change	RNAi phenotype*	Reference
F09F7.4	Enoyl-CoA hydratase	1.8	Emb	[61]
			Gro	[19]
F22A3.6	Unknown	1.8	Emb	[62]
T15B7.1	Ficolin and related extracellular proteins	1.7	Emb	[63]
F52B11.4	Collagen (col-133)	1.7	Emb, Gro, Rup	[19]
R11G11.14	Triglyceride lipase-cholesterol esterase	1.6	Him	[64]
C55B7.4	Acyl CoA dehydrogenase (acdh-1)	1.5	Age	[65]
C25G4.6	Unknown	1.5	Ste	[66]
			Lva, Pvl, Stp	[67]
T04A8.5	Glutamine phosphoribosylpyrophosphate amidotransferase	1.5	Larval lethal-early (L1/L2), WT	[61]
			Lva	[63]

*The phenotypes are: Age, ageing alteration; Emb, abnormal embroygenesis; Gro, abnormal growth rate; Him, high incidence of males; Lva, larval arrest; Pvl, protruding vulva; Rup, exploded through vulva; Ste, sterile; Stp, sterile progeny; WT, wild type.

ISSN: 1474-760X