The Sas3p and Gcn5p histone acetyltransferases are recruited to similar genes

Table 4 Genes that showed a significantly decreased H3K14 acetylation level in the sas3Δ mutant

GO attribute	No. of genes in category	No. of genes	P value
Cell cycle/cell-division cycle	397	54	2.8 × 10^-7
Mitotic cell cycle	233	37	5.8 × 10^-7
Cell budding/budding	77	18	2.2 × 10^-6
Development	365	48	3.7 × 10^-6
Reproduction	251	36	9.5 × 10^-6
Plasma membrane/bacterial inner membrane/cell membrane/cytoplasmic membrane/juxtamembrane/Plasmalemma	232	34	1.1 × 10^-6
Cell organization and biogenesis	1,149	111	1.6 × 10^-5
Cytoskeleton organization and biogenesis	288	39	1.6 × 10^-5

Groups of genes that showed a significantly decreased H3K14ac level in the sas3Δ mutant relative to the wild-type strain (434 genes) were classified based on over-represented attributes using the FuncAssociate web tool [52]. The number of genes bound for every category, the number of overall genes with this attribute and P values are shown. Only the eight categories with the most significant P values are shown. The search for GO categories was done using the FuncAssociate server [52].

ISSN: 1474-760X