Figure 5
From: A functional map of NFκB signaling identifies novel modulators and multiple system controls
Contextual organization of the NFκB negative modulators. Organization was determined on the basis of follow-up screens with an IKBKB constitutively-active mutant. If activation of the NFκB reporter was blocked by the negative modulator (≥ 70% average reduction), the negative modulator was considered downstream of the constitutively active mutant. If activation of the NFκB reporter was not blocked, the negative modulator was considered unclassified as to its inhibitor influence.