Figure 1From: A functional map of NFκB signaling identifies novel modulators and multiple system controlsFlowchart outlining the steps in the gain-of-function and loss-of-function genomic screens. The gain-of-function screen was used to identify positive modifiers of the NFκB signaling pathway and the loss-of-function screen was used to identify negative modifiers. Approximately 14,500 full-length human and mouse genes were screened for activity.Back to article page