Figure 2

The distribution of pseudogenes is uneven in the genome and across functional categories. (a) Pseudogenes are more likely to be found near genomic breakpoints than in the rest of the genome. B. Genes inactivated both in Schu S4 and live vaccine strain (LVS) and sharing the same inactivating mutation are more likely to be near a genomic breakpoint than those not sharing the same inactivating mutation. (c) Missing and inactivated genes in the genomes of Francisella tularensis subspecies tularensis (F.t.t.) Schu S4 and Francisella tularensis subspecies holarctica (F.t.h.) LVS are not evenly distributed across functional categories. F.t.n., Francisella tularensis subspecies novicida; kb, kilobases; LPS, lipopolysaccharide.