|
E2F3 gene signature
| | | |
|
E2F
|
DP-1, E2F, p53
|
DP-1, E2F
|
<0.001
|
|
Caspases
|
CREB, Max, SRF, p53, AP-2α
|
AP-2α
|
<0.001
|
|
Myc gene signature
| | | |
|
AhR
|
AhR, ER-α, Sp1, p300, NF-κB, Arnt
|
AhR, Sp1, NF-κB, Arnt
|
<0.001
|
|
HIF-1
|
p53, p300, HIF-1α, HNF-4α2, Arnt
|
HIF-1α, Arnt
|
<0.001
|
|
Notch
|
Max, LEF-1, p300, c-Myc
|
Max, c-Myc
|
<0.001
|
|
EGF
|
c-Fos, Elk-1, Sp1, STAT3, c-Jun, STAT1α, c-Myc
|
Sp1, c-Myc
|
0.002
|
|
Caspases
|
CREB, Max, SRF, p53, AP-2α
|
Max, AP-2α
|
0.002
|
|
c-Kit
|
MITF, Sp1, Tal-1, p300, GATA-1
|
MITF, Sp1, Tal-1
|
0.006
|
|
Ras gene signature
| | | |
|
AhR
|
AhR, ER-α, Sp1, p300, NF-κB, Arnt
|
Sp1, NF-κB
|
<0.001
|
|
Apoptosis
|
p53, FOXO3a, NF-κB
|
p53, NF-κB
|
0.001
|
|
Caspases
|
CREB, Max, SRF, p53, AP-2α
|
CREB, p53, AP-2α
|
0.004
|
|
RANK
|
MITF, PU.1, c-Jun, NF-κB
|
PU.1, NF-κB
|
0.008
|
|
TNFα
|
AP-1, NF-κB
|
AP-1, NF-κB
|
0.009
|
|
TLR4
|
CREB, CRE-BP2, STAT1, Elk-1, p300, IRF-3, IRF-7, NF-κB
|
CREB, CRE-BP2, NF-κB
|
0.015
|
|
MAPK
|
CREB, Elk-1, p53, c-Jun, c-Myc
|
CREB, p53
|
0.023
|
|
TLR3
|
CRE-BP2, p300, c-Jun, IRF-3, IRF-7, NF-κB
|
CRE-BP2, NF-κB
|
0.034
|
|
p38
|
ELk-1, p53, MITF, PPAR-α, CHOP-10, Max, CREB, PU.1, MRF4, HNF-1α, CRE-BP2, NF-AT2, STAT3
|
p53, PPAR-α, CHOP-10, CREB, PU.1, CRE-BP2
|
0.035
|
|
Stress
|
PPAR-γ, c-Ets-1, PPAR-α, Max, NF-AT2, HSF1, c-Jun, Elk-1, p53, CHOP-10, CREB, CRE-BP2, RXR-α, HNF-1α, STAT3, MRF4
|
PPAR-α, p53, CHOP-10, CREB, CRE-BP2
|
0.037
|
