Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors

Table 2 Gene set enrichment analysis of the ten murine groups versus five human subtypes

		Basal-like		Luminal		HER2+/ER-		Normal		Claudin-low
Mouse class	No. of genes	p value	p value	p value	p value	p value	p value	p value	p value	p value	p value
Is class
I	1,882	-	-	0.4625	0.8755	0.5388	0.9137	0.1659	0.5628	0.0048	0.1028
II	912	-	-	-	-	0.5867	0.9609	-	-	0.0021	0.001
III	143	0.5289	0.9048	-	-	0.5285	0.9047	0	0.008	-	-
IV	1,019	0	0.0581	-	-	-	-	-	-	-	-
V	34	-	-	0.8492	0.998	0.9324	0.999	-	-	0.0427	0.09274
VI	820	-	-	0.0062	0.0783	0.3536	0.7864	0.8653	0.9769	-	-
VII	851	0.1258	0.3768	-	-	0.5616	0.9137	-	-	-	-
VIII	236	0.1449	0.6098	0.3483	0.8205	-	-	0.01878	0.2349	-	-
IX	462	0.0019	0.004	-	-	0.56	0.9509	-	-	-	-
X	338	0	0.001	-	-	0.9275	0.998	-	-	-	-
Is not class
I	1,882	0.0128	0.1662	-	-	-	-	-	-	-	-
II	912	0.3996	0.8348	0.8601	0.999	-	-	0.3602	0.7655	-	-
III	143	-	-	0.3178	0.7259	-	-	-	-	0.7628	0.991
IV	1,019	-	-	0.1833	0.6516	0.398	0.8427	0.2241	0.7255	0.1453	0.6116
V	34	0.86	1	-	-	-	-	0.0656	0.1653	-	-
VI	820	0	0.04	-	-	-	-	-	-	0.1043	0.4444
VII	851	-	-	0.1733	0.5151	-	-	0.5403	0.9128	0.1628	0.5215
VIII	236	-	-	-	-	0.1131	0.5305	-	-	0.6427	0.961
IX	462	-	-	0.04305	0.0833	-	-	0.022	0.037	0.2612	0.5936
X	338	-	-	0.02236	0.0682	-	-	0.1313	0.3717	0.5437	0.9489

ISSN: 1474-760X