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Table 2 Gene set enrichment analysis of the ten murine groups versus five human subtypes

From: Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors

  

Basal-like

Luminal

HER2+/ER-

Normal

Claudin-low

Mouse class

No. of genes

p value

p value

p value

p value

p value

p value

p value

p value

p value

p value

Is class

           

I

1,882

-

-

0.4625

0.8755

0.5388

0.9137

0.1659

0.5628

0.0048

0.1028

II

912

-

-

-

-

0.5867

0.9609

-

-

0.0021

0.001

III

143

0.5289

0.9048

-

-

0.5285

0.9047

0

0.008

-

-

IV

1,019

0

0.0581

-

-

-

-

-

-

-

-

V

34

-

-

0.8492

0.998

0.9324

0.999

-

-

0.0427

0.09274

VI

820

-

-

0.0062

0.0783

0.3536

0.7864

0.8653

0.9769

-

-

VII

851

0.1258

0.3768

-

-

0.5616

0.9137

-

-

-

-

VIII

236

0.1449

0.6098

0.3483

0.8205

-

-

0.01878

0.2349

-

-

IX

462

0.0019

0.004

-

-

0.56

0.9509

-

-

-

-

X

338

0

0.001

-

-

0.9275

0.998

-

-

-

-

Is not class

           

I

1,882

0.0128

0.1662

-

-

-

-

-

-

-

-

II

912

0.3996

0.8348

0.8601

0.999

-

-

0.3602

0.7655

-

-

III

143

-

-

0.3178

0.7259

-

-

-

-

0.7628

0.991

IV

1,019

-

-

0.1833

0.6516

0.398

0.8427

0.2241

0.7255

0.1453

0.6116

V

34

0.86

1

-

-

-

-

0.0656

0.1653

-

-

VI

820

0

0.04

-

-

-

-

-

-

0.1043

0.4444

VII

851

-

-

0.1733

0.5151

-

-

0.5403

0.9128

0.1628

0.5215

VIII

236

-

-

-

-

0.1131

0.5305

-

-

0.6427

0.961

IX

462

-

-

0.04305

0.0833

-

-

0.022

0.037

0.2612

0.5936

X

338

-

-

0.02236

0.0682

-

-

0.1313

0.3717

0.5437

0.9489

  1. Statistically significant findings are highlighted in bold. NOM = nominal.
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Genome Biology

ISSN: 1474-760X

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