Skip to main content

Advertisement

Table 2 Gene set enrichment analysis of the ten murine groups versus five human subtypes

From: Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors

   Basal-like Luminal HER2+/ER- Normal Claudin-low
Mouse class No. of genes p value p value p value p value p value p value p value p value p value p value
Is class            
I 1,882 - - 0.4625 0.8755 0.5388 0.9137 0.1659 0.5628 0.0048 0.1028
II 912 - - - - 0.5867 0.9609 - - 0.0021 0.001
III 143 0.5289 0.9048 - - 0.5285 0.9047 0 0.008 - -
IV 1,019 0 0.0581 - - - - - - - -
V 34 - - 0.8492 0.998 0.9324 0.999 - - 0.0427 0.09274
VI 820 - - 0.0062 0.0783 0.3536 0.7864 0.8653 0.9769 - -
VII 851 0.1258 0.3768 - - 0.5616 0.9137 - - - -
VIII 236 0.1449 0.6098 0.3483 0.8205 - - 0.01878 0.2349 - -
IX 462 0.0019 0.004 - - 0.56 0.9509 - - - -
X 338 0 0.001 - - 0.9275 0.998 - - - -
Is not class            
I 1,882 0.0128 0.1662 - - - - - - - -
II 912 0.3996 0.8348 0.8601 0.999 - - 0.3602 0.7655 - -
III 143 - - 0.3178 0.7259 - - - - 0.7628 0.991
IV 1,019 - - 0.1833 0.6516 0.398 0.8427 0.2241 0.7255 0.1453 0.6116
V 34 0.86 1 - - - - 0.0656 0.1653 - -
VI 820 0 0.04 - - - - - - 0.1043 0.4444
VII 851 - - 0.1733 0.5151 - - 0.5403 0.9128 0.1628 0.5215
VIII 236 - - - - 0.1131 0.5305 - - 0.6427 0.961
IX 462 - - 0.04305 0.0833 - - 0.022 0.037 0.2612 0.5936
X 338 - - 0.02236 0.0682 - - 0.1313 0.3717 0.5437 0.9489
  1. Statistically significant findings are highlighted in bold. NOM = nominal.