Tumor model | No. of tumors | Specificity of lesions | Experimental oncogenic lesion(s) | Strain | Reference |
---|---|---|---|---|---|
TgWAP-Myc | 13 | WAP* | cMyc overexpression | FVB | [60] |
TgWAP-Int3 | 7 | WAP | Notch4 overexpression | FVB | [61] |
TgWAP-T 121 | 5 | WAP | pRb, p107, p130 inactivation | B6D2 | [37] |
TgWAP-T 121 | 2 | WAP | pRb, p107, p130 inactivation | BALB/cJ | [37] |
TgWAP-Tag | 5 | WAP | SV40 L-T (pRb, p107, p130, p53, p300 inactivation, others); SV40 s-t | C57Bl/6 | [62] |
TgC3(1)-Tag | 8 | C3(1)†| SV40 L-T (pRb, p107, p130, p53, p300 inactivation, others); SV40 s-t | FVB | [63] |
TgMMTV-Neu | 10 | MMTV‡ | Unactivated rat Her2 overexpression | FVB | [64] |
TgMMTV-Wnt1 | 11 | MMTV | Wnt 1 overexpression | FVB | [65] |
TgMMTV-PyMT | 7 | MMTV | Py-MT (activation of Src, PI-3' kinase, and Shc) | FVB | [66] |
TgMMTV-Cre;Brca1Co/Co;p53+/- | 10 | MMTV | Brca1 truncation mutant; p53 heterozygous null | C57Bl/6 | [67] |
p53-/-transplanted | 5 | None | p53 inactivation | BALB/cJ | [68] |
Medroxyprogesterone-DMBA-induced | 11 | None | Random DMBA-induced | FVB | [69] |
p53+/-irradiated | 7 | None | p53 heterozygous null, random IR induced | BALB/cJ | [70] |
Brca1+/-;p53+/-irradiated | 7 | None | Brca1 and p53 heterozygous null, random IR induced | BALB/cJ | [1] |