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Table 3 Genes related to oligodendrocyte differentiation are differentially expressed in Nfia-/- mice at P16

From: Gene expression analysis of nuclear factor I-A deficient mice indicates delayed brain maturation

Gene name

Fold change of mRNA expression in Nfia-/- versus Nfia+/+ micea

Reference

Genes typically expressed in oligodendrocyte precursors or related to de-differentiation of precursor cells

   Hmgb2

1.92

[45]

   Sox2

1.28

[46]

   Sox4

1.33/1.44

[47]

   Sox11

1.88/2.22

[47]

   Tenascin-C

1.47

[48]

   Myef2b

1.2

[39]

Genes typically expressed in mature oligodendrocytes or related to terminal oligodendrocyte differentiation

   Mobp

-2.11/-2.10/-1.99/-1.98

[49]

   Mal

-2.43

[50]

   Mog

-1.95

[51]

   Claudin 11

-1.67

[52]

   Plp1

-1.58

[53]

   Ugt8

-1.54/-1.45

[50]

   Mag

-1.52

[53]

   Dio2c

-1.43

[38]

   Car2

-1.35

[54]

  1. aAccording to microarray analysis; for genes represented by more than one probe set, the individual fold changes for each probe set are given. bIndirect link to oligodendrocyte maturation (My-EF2 can repress expression of myelin basic protein). cIndirect link to oligodendrocyte maturation (Dio2 catalyzes thyroxine to tri-iodothyronine conversion, and tri-iodothyronine triggers terminal differentiation of oligodendrocytes). P16, postnatal day 16.
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Genome Biology

ISSN: 1474-760X

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