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Table 1 Genes strongly dysregulated in P16 Nfia-/- mice

From: Gene expression analysis of nuclear factor I-A deficient mice indicates delayed brain maturation

Affymetrix probe set ID fold change P value Gene (encoded protein)
92939_at -3.22 0.0026 Gabra6 (γ-aminobutyric acid [GABA]-A receptor, subunit α6)
92940_s_at -2.94 0.0018 Gabra6 (GABA-A receptor, subunit α6)
100068_at -3.14 0.0075 Aldh1a1 (aldehyde dehydrogenase family 1, subfamily A1)
99089_at -2.43 0.0007 Mal (myelin and lymphocyte protein, T-cell differentiation protein)
101887_at -2.24 0.0007 Agt (angiotensinogen precursor, gene, exon 5 and complete coding sequence)
93137_at -2.21 0.0003 Ntsr2 (neurotensin receptor 2)
103023_at -2.13 0.0003 Lcat (lecithin cholesterol acyltransferase)
99046_at -2.11 0.0080 Mobp (myelin-associated oligodendrocytic basic protein)
100536_at -2.10 0.0048 Mobp (myelin-associated oligodendrocytic basic protein)
99047_at -1.99 0.0011 Mobp (myelin-associated oligodendrocytic basic protein)
99048_g_at -1.98 0.0022 Mobp (myelin-associated oligodendrocytic basic protein)
94391_at -2.07 0.0014 Gjb6 (gap junction membrane channel protein β6)
102571_at -1.81 0.0194 Gjb6 (gap junction membrane channel protein β6)
97089_at -2.06 0.0128 Folh1 (folate hydrolase)
160754_at -1.97 0.0059 Pygm (muscle glycogen phosphorylase)
103987_at -1.95 0.0044 Mog (myelin oligodendrocyte glycoprotein)
101467_at -1.90 0.0018 S100b (mouse S100 β protein exons 1 to 3, complete cds.)
100002_at -1.89 0.0016 Itih3 (inter-α trypsin inhibitor, heavy chain 3)
95286_at -1.88 0.0112 Clu (clusterin)
161294_f_at -1.63 0.0093 Clu (clusterin)
100494_at -1.87 0.0003 Fgf1 (fibroblast growth factor 1)
97317_at -1.81 0.0003 Enpp2 (ectonucleotide pyrophosphatase/phosphodiesterase 2)
94144_g_at -1.71 0.0053 GFAP (mouse gene for glial fibrillary acidic protein)
94143_at -1.56 0.0279 GFAP (mouse gene for glial fibrillary acidic protein)
160065_s_at -1.70 0.0066 Csrp1 (cysteine and glycine-rich protein 1)
92608_at -1.63 0.0194 Csrp1 (cysteine and glycine-rich protein 1)
94057_g_at -1.70 0.0227 Scd1 (stearoyl-CoA desaturase; Mouse stearoyl-CoA desaturase gene, exon 6)
94056_at -1.68 0.0093 Scd1 (stearoyl-CoA desaturase; Mouse stearoyl-CoA desaturase gene, exon 6)
161610_at -1.69 0.0053 Ndrg2 (N-myc downstream regulated 2)
96088_at -1.68 0.0021 Ndrg2 (N-myc downstream regulated 2)
94079_at -1.68 0.0035 Sept4 (septin 4)
92717_at -1.68 0.0135 Neurod1 (Neurogenic differentiation 1)
93389_at -1.67 0.0026 Prom1 (prominin 1)
93390_g_at -1.67 0.0043 Prom1 (prominin 1)
98872_at -1.67 0.0129 Ugt8 (UDP-galactose:ceramide galactosyltransferase [Cgt] gene)
93573_at -1.67 0.0396 Mt1 (mouse gene for metallothionein-I [three exons])
96720_f_at -1.66 0.0145 Pvalb (Parvalbumin)
100441_s_at -1.64 0.0014 Ank1 (ankyrin 1, erythroid)
103429_i_at -1.61 0.0060 (Expressed sequence AL024210)
93750_at -1.58 0.0011 Gsn (murine gelsolin protein; mouse gelsolin gene, complete cds.)
100044_at -1.58 0.0196 Cldn11 (claudin 11)
93159_at -1.54 0.0065 Expressed sequence tags
92802_s_at -1.54 0.0333 Plp1 (Proteolipid protein [myelin] 1)
92932_at -1.52 0.0059 Cbln1 (cerebellin 1 precursor protein)
102405_at -1.52 0.0111 MAG (myelin-associated glycoprotein)
98338_at -1.52 0.0363 En2 (engrailed 2)
98025_at -1.51 0.0147 Evi2a (ecotropic viral integration site 2a)
93664_at -1.51 0.0272 Atp1b2 (ATPase, Na+/K+ transporting, β2 polypeptide)
102773_at -1.50 0.0246 Car8 (carbonic anhydrase 8)
103046_at -1.50 0.0079 Car4 (Mus musculus carbonic anhydrase IV gene, complete cds.)
95654_at 1.50 0.0376 Clic1 (chloride intracellular channel 1)
92380_r_at 1.58 0.0092 Ptprz1 (protein tyrosine phosphatase, receptor type, Z polypeptide 1)
92379_f_at 1.82 0.0020 Ptprz1 (protein tyrosine phosphatase, receptor type, Z polypeptide 1)
98394_at 1.58 0.0401 Dlx1 (distal-less homeobox 1)
97527_at 1.65 0.0083 Cks2 (CDC28 protein kinase regulatory subunit 2)
97520_s_at 1.66 0.0217 Nnat (neuronatin)
98038_at 1.72 0.0004 Hmgb3 (high mobility group box 3)
101503_at 1.73 0.0339 Dpysl3 (dihydropyrimidinase-like 3)
93028_at 1.77 0.0278 H19 (H19 fetal liver mRNA)
100600_at 1.84 0.0030 CD24a (CD24a antigen)
102307_at 1.87 0.0085 Dcx (doublecortin)
101631_at 1.88 0.0169 Sox11 (SRY-box containing gene 11)
93669_f_at 2.22 0.0029 Sox11 (SRY-box containing gene 11)
93250_r_at 1.92 0.0004 Hmgb2 (high mobility group box 2)
96041_at 1.98 0.0037 Rbm3 (RNA binding motif protein 3)
98967_at 2.59 0.0002 Fabp7 (fatty acid binding protein 7, brain)
  1. Provided is a list of genes significantly dysregulated more than 1.5-fold in Nfia-/- mouse brain relative to Nfia+/+ mice at postnatal day 16 (P16). Note that several genes (for instance, Gabra6) are represented by more than one Affymetrix probe set.