|
Statistic
|
Embryoid blast
|
Myeloid
|
|---|
| |
4 hours
|
24 hours
|
4 hours
|
24 hours
|
|---|
|
Standard t (scheme 1)
|
32
|
8,038
|
7,154
|
331
|
|
Cyber t (scheme 2)
|
1,288
|
9,769
|
10,349
|
4,464
|
|
Scheme 4
|
90
|
87
|
268
|
38
|
|
SAM
|
4,954
|
14,239
|
16,644
|
9,392
|
- Each entry in this table is the number of significant genes when comparing treatment (DMSO + drug) with control (just DMSO) for a cell type (embryoid blast or myeloid) and a time point (4 or 24 hours). All data were subject to quantile-quantile normalization and summarized using RMA. The Benjamini and Hochberg algorithm was used on P values generated by the standard t test, cyber t, and scheme 4 to calculate false discovery rate. The values for SAM were generated by the TIGR Multiple Array Viewer (see Materials and methods) with 100 permutations and the default parameters. DMSO, dimethyl sulfoxide; RMA, Robust Multichip Average; SAM, significance analysis of microarrays.
