Statistic | Embryoid blast | Myeloid |
|---|
| Â | 4 hours | 24 hours | 4 hours | 24 hours |
|---|
Standard t (scheme 1) | 32 | 8,038 | 7,154 | 331 |
Cyber t (scheme 2) | 1,288 | 9,769 | 10,349 | 4,464 |
Scheme 4 | 90 | 87 | 268 | 38 |
SAM | 4,954 | 14,239 | 16,644 | 9,392 |
- Each entry in this table is the number of significant genes when comparing treatment (DMSO + drug) with control (just DMSO) for a cell type (embryoid blast or myeloid) and a time point (4 or 24 hours). All data were subject to quantile-quantile normalization and summarized using RMA. The Benjamini and Hochberg algorithm was used on P values generated by the standard t test, cyber t, and scheme 4 to calculate false discovery rate. The values for SAM were generated by the TIGR Multiple Array Viewer (see Materials and methods) with 100 permutations and the default parameters. DMSO, dimethyl sulfoxide; RMA, Robust Multichip Average; SAM, significance analysis of microarrays.
