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Table 7 Estimation of the subcellular proteomes of eight eukaryotic organisms

From: ngLOC: an n-gram-based Bayesian method for estimating the subcellular proteomes of eukaryotes

  Yeast (S. cerevisiae) Worm (C. elegans) Fruitfly (D. melano) Mosquito (A. gambiae) Zebrafish (D. rerio) Chicken (G. gallus) Mouse (M. musculus) Human (H. sapiens) Range
Proteome 5,799 22,400 13,649 15,145 13,803 5,394 33,043 38,149  
GO annotated 5,486 12,357 9,997 8,847 10,106 4,363 23,744 24,638  
% ngLOC coverage 97.48 94.92 96.73 97.94 98.64 9,9.82 94.79 94.52 94.79-99.82
Proteome estimated 5,653 21,262 13,203 14,833 13,616 5,384 31,320 36,059  
% CYT 15.22 14.80 12.74 14.43 15.01 13.66 13.44 14.14 12.74-15.22
% CSK 1.07 1.19 1.05 1.11 1.31 1.24 1.50 1.48 1.05-1.50
% END 2.71 3.47 2.85 3.25 3.34 2.53 2.99 3.04 2.53-3.47
% EXC 8.88 12.60 12.26 14.28 9.91 12.65 11.52 11.71 8.88-14.28
% GOL 1.48 1.31 1.40 1.07 1.68 1.47 1.52 1.56 1.07-1.68
% LYS 0.11 0.58 0.55 0.53 0.65 0.44 0.59 0.67 0.11-0.67
% MIT 9.55 5.84 4.86 5.52 4.72 4.16 4.24 4.80 4.16-9.55
% NUC 33.53 29.75 37.38 29.50 30.31 28.24 27.35 28.38 27.35-37.38
% PLA 16.19 24.41 20.06 21.36 21.66 22.78 27.18 24.08 16.19-27.18
% POX 0.54 0.66 0.42 0.48 0.51 0.25 0.44 0.46 0.25-0.66
% Single-localized 89.29 94.60 93.59 91.53 89.11 87.42 90.77 90.32  
% Multi-localized 10.71 5.40 6.41 8.47 10.89 12.58 9.23 9.68  
% CYT-NUC 6.49 2.36 2.76 3.44 5.40 6.27 4.51 4.74  
  1. This chart presents the location-wise percentages of the proteome predicted to localize into one organelle. (For example, 9.55% of the yeast proteome is localized to the mitochrondria only.) These percentages sum to the total size of the proteome estimated to be single-localized. We also present the estimated percentage of the proteome that is localized to multiple organelles. The percentage of the proteome estimated to localize to both the cytoplasm and nucleus is also displayed. The coverage is determined with a confidence score (CS) threshold of 15. Multi-localized sequences are determined with a multi-localized confidence score (MLCS) threshold of 60. CSK, cytoskeleton; CYT, cytoplasm; END, endoplasmic reticulum; EXC, extracellular; GO, Gene Ontology; GOL, golgi; LYS, lysosome; MIT, mitochondria; NUC, nucleus; PLA, plasma membrane; POX, perixosome.