Figure 4

Selected GO annotations of genes differentially expressed in α-MHC⁺ cells. Shown are selected Gene Ontology (GO) annotations (biologic process [BP]) of genes that are differentially expressed in α-MHC⁺ cells as compared with the 15-day-old embryoid bodies (EBs) and compared with the α-MHC embryonic stem (ES) cells. A total of 1,845 probe set IDs, which were differentially expressed in α-MHC⁺ cells, were converted to Genbank accessions and redundancies were removed. SOURCE was used to obtain GO BP annotations. Genesis was used to visualize and identify GO BP categories of interest and extract corresponding lists of transcripts. (a) The pie chart shows the distribution of these annotations. (b) The bar chart shows the number of genes in the categories adhesion, cell cycle, cell death, cell-cell signalling, cellular metabolism, development, stress response, signal transduction, transcription, and transport separately for upregulated and downregulated transcripts.