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Figure 3 | Genome Biology

Figure 3

From: Statistical tools for synthesizing lists of differentially expressed features in related experiments

Figure 3

Typical plots of T(q) and R(q) in the case of independent experiments. The two independent experiments are simulated under scenario I, structure A, with true differences drawn from a Ga(1, 1) and noise experiment specific of 2 and 2.5, respectively (signal-to-noise ratio = 0.4). The left plot shows the distribution of T(q) and the right one shows the distribution of R(q) with Bayesian credibility intervals at 95%. T(q) follows a horizontal line of height 1 (independence between the lists) and presents instability for small p values (left tail). The Bayesian model does not present any significant threshold for which R(q) deviates from 1 and the CI95 always includes 1.

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