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Figure 1 | Genome Biology

Figure 1

From: Statistical tools for synthesizing lists of differentially expressed features in related experiments

Figure 1

Typical plots of T(q) and R(q) for associated experiments (case A1). The two associated experiments were simulated under scenario I, structure A, with true differences drawn from a Ga(2.5,0.4) and noise experiment specific of 0.5 and 0.8, respectively (signal-to-noise ratio = 9.6). The left plot shows the distribution of T(q) and the right one shows the distribution of R(q) with Bayesian credibility intervals at 95%. T(q) shows a deviation from 1 for a p value between 0.01 and 0.5. T(qmax) is 2.6 and corresponds to a threshold q = 0.01. R(q) presents the same trend, but the estimates are slightly smaller since the model takes into account the variability of the margins of the 2 × 2 table. The threshold associated with R(q) = 2 is 0.08. The number of genes in common for each ratio R(q) is reported on the right axis of each plot.

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