Figure 5

Proportion of each CNE sequence that overlaps the counterpart co-ortholog CNE. Main graph: for each overlapping pair of co-orthologous CNEs (involving just two sequences), the proportion of the full length of each CNE (P1-P2) made up by the overlap was calculated using the human sequence as the reference. The larger of the two proportions was always plotted as P1 to simplify analysis. Inset bar chart: summary of the number of overlapping CNE pairs falling into three main proportion categories: P1 ≥ 0.8, P2 ≥ 0.8 - pairs that overlapped over the majority of both elements, suggesting little evolution of element length since duplication; P1 ≥ 0.8, P2 < 0.8 - pairs that have undergone significant degeneration in element length in one of the copies compared to its counterpart; P1 < 0.8, P2 < 0.8 - pairs that have undergone a level of degeneration in element length in both copies at their edges.